A facile synthesis of [ ' * C ] epicholesterol
نویسندگان
چکیده
A facile procedure is described for the preparation of [ "C]epicholesterol from [ '*C]cholesteroL Cholesterol is first converted to cholesteryl mesylate, which is treated with cesium acetate and 18-crown-6 in refluxing toluene to give epicholesteryl acetate. The latter is hydrolyzed, without isolation, with potassium hydroxide in tetrahydrofuran-methanol to give epicholesterol, which is obtained in pure form by preparative thin-layer chromatography. -Yan, J., and R. Bittman. A facile synthesis of ['*C]epicholesterol. J. Lipid Res. 1990. 31: 160-162.
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A facile synthesis of [14C] epicholesterol.
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